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Xanax would calm me down a bit, but not stop my aggrivation, or quick temper. I am running into the same thing for a total different reason and I am on zoloft for pmdd and post tubal ligation syndrome and its not helping so I am not sure what to do. When my Zoloft dosage was raised to 100mg from 50mg I started to experience unpleasant side effects. Mainly the inability to sleep, no sex drive, leg tremors, and yellow fingernails. Does ciprofloxacin treat chlamydia Should i order viagra online Doxycycline expiration Premenstrual dysphoric disorder PMDD is a severe and disabling form of premenstrual syndrome affecting 3–8% of menstruating women. The disorder consists of a "cluster of affective, behavioral and somatic symptoms" that recur monthly during the luteal phase of the menstrual cycle. 1 purchase cytotec (misoprostol) Zoloft can help in PMS premenstrual syndrome, freeing you from the emotional and psychological symptoms of PMS. Zoloft, either taken alone or with other mood. 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