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Tamoxifen uterine thickening

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  1. mr_jazz New Member

    Tamoxifen uterine thickening


    Hi ladies I wrote a post a few weeks ago regarding my concerns of having some unwelcome symptoms due to tamoxifen, i.e bloating, left side abdominal pain. Over the last few weeks I have had firstly an ultrasound and internal ultrasound which showed uterus had thickened and a cyst on left ovary, so to follow up had an MRI last week and then a hysteroscopy yesterday and I've had blood works done, ca125 being one of them which is a tumour biomarker. So..MRI apparently shwed a 6cm cyst on ovary and a polyp in uterus. The gynae yesterday during hysteroscopy was fully expecting to find this polyp but couldn't, all she could seem to find was what she called a lot of scarring within the uterus/womb and said she couldn't understand why/how it was there, so she's taken biopsies and I should get results in a week. She said that she was concerned as my womb didn't look how she expected based on MRI results and was of the feeling it could be 'something a bit scarier', she later clarified poss endometrial cancer which is a risk, although apparently a low one of tamoxifen. I am completely freaked out now, had no bleeding ever whilst on tamoxifen, my periods stopped on chemo in oct 2015. So the thing that really made me go docs was left sided pain which is a cyst! how do i buy clomid I had a lumpectomy in April 2006; 8 rounds of chemo and 34 radiation treatments. I have not had a 'period' since August 2006 and I am now 42 this week. I went to have a uterine ultrasound to see if I am still fertile to have another child and my OBGYN noticed a thickening of my uterine lining at a 15 and some cyctlike things on the lining. Also, two cycts on the one ovary and she said that we should think positively that the ovary is 'active'. My breast cancer was a mucuous carsomina; stage 1c, well differentiated. I am scheduled to have a D&C on Friday and am so scare that is could be some form of cancer. My OBGYN just wants to be safe and ordered to have the D&C performed. Hi, Well, nothing can be said about the chances before the examination is done and the lab analysis reports come in. Tamoxifen is known to cause benign endometriosis as well as endometrial cancer - only investigatons will help to come to a definite diagnosis. If you want to go ahead and plan a pregnancy after your reports come in and hopefully they turn out ok, you should talk to your doctor/ oncologist and discontinue taking tamoxifen.

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    Using a non hormonal intrauterine device IUD or coil has also been linked with a decreased risk of womb cancer. Diabetes. Several studies show a higher risk of womb cancer in women with diabetes, for both Type 1 and Type 2. how can i buy viagra without seeing a doctor Consequently, a large number of women will be subjected to both the benefits and potential risks of long-term tamoxifen therapy. One of the most significant potential complications is the development of endometrial cancer. The estimated annual risk of endometrial cancer in tamoxifen-treated patients is approximately 2 per 1,000 women. Breast cancer is the most common life-threatening cancer among women in British Columbia and the second most common cause of cancer mortality.

    Maeve wrote: Hi, Just been for a smear (PAP) test today and the nurse told me I had an unusually thickend lining on my cervix, I know that Tamox. can interfere with the uterus in different ways but just wondered if anyone experienced the same problem. I've been on tamoxifen for just over 18 months and would love to her from anyone who has had uterus problems as a result of tamoxifen. Many Thanks Feb 23, 2009 AM kuchagirl wrote: Hi, My endometrial lining thickened up considerably around 10 months after I started Tamoxifen, as seen on ultrasound. My gynecologist says there's nothing to worry about. Also, I've googled around for medical studies on Tamoxifen's impact on the endometrial lining, and it is normal for the endometrial lining to thicken and to stay thickened as long as the patient is on Tamoxifen. I did have one episode of spotting (which led to an ultrasound which showed the thickened lining), but have not had any spotting at all in 12 months. This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer The paragard iud is hormone free. It works by creating a toxic environment for sperm preventing fertilization. Because it is hormone free it has no real effect on the endometrial lining. It does not thin it out like Mirena (levonorgestrel) but also does not thicken it either. Read more See 1 more doctor answer Your gynecologist must discuss this with you as soon as possible. Read more Thickening of the endometrium during a normal menstrual cycle is due to estrogen prodcution by a follicle (which can appear as a cyst on ultrasound). There are many ways to determine if things are OK or not and the gynecologist will help you. There are some other cysts, like a granulosa cell tumor that also can make estrogen and thicken the endometrium. Polyps, fibroids and other conditions can also make the lining appear thicker on ultrasound. Read more It may be time for a hysterosalpingogram (HSG) or sono HSG to ensure there isn't another process occurring.

    Tamoxifen uterine thickening

    Endometrial Thickness in Post Menopausal, The Effect of Tamoxifen on the Endometrium Cancer Network

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  4. Regardless of the cutoff value for detecting endometrial abnormalities, the most common endometrial transvaginal US pattern seen in women treated with tamoxifen is a thickened endometrium with cystic spaces described as a ‘Swiss cheese’ pattern 10–12,27,71–76 Fig. 1.

    • The effect of tamoxifen on the genital tract
    • Breast - BC Cancer
    • OVARIAN CANCER Personal Stories

    A Pap smear is a simple, quick, and essentially painless screening test procedure for cancer or precancer of the uterine cervix. Cells collected from a woman's cervix during a pelvic exam are spread on a microscope slide for examination.; The cells are evaluated for abnormalities, specifically for pre- cancerous and cancerous changes. inderal la 160 I also had uterine lining thickening on ultrasound -- it was actually 18mm, and had a biopsy. It came back normal -- proliferative endometrium is not necessarily thickening if you are premenopausal -- it is the phase of your cycle where it is supposed to thicken -- with tamoxifen it just thickens a little bit more. P.s ca125 came back well within normal range, I was under impression it was just for ovarian cancer but can detect other cancers within the body i.e uterine/endometrial. I started tamoxifen 2 years ago.

     
  5. atet1986 New Member

    I was on it for about six years (first three on brand name - there was no generic yet) then on generic and it stopped working (unrelated situation). However, as you mentioned above, the only thing consistent between generics is the active ingredients, every generic has a different mix of inactive and binding agents. If you can afford it, brand name is great, but if not, there are many different companies that make generic sertraline now, so one bad generic doesn't mean all are bad. After doing a Google search, I was able to confirm that Inosert is one company's brand name for generic Zoloft (sertraline). Since I couldn't find very many websites referencing or describing Inosert, I am somewhat skeptical about it. Basically, my question is: "Is Inosert a safe and valid chemical equivalent to Zoloft? I'm 6 weeks pregnant 3rd pregnancy and my last pregnancy I was prescribed that it's the generic name for Zoloft and it is better to take wile being pregnant than prosac there is nothing to worry about when it comes to this medication my child ha no birth defect so your in the clear but if you are not certain than consult with a doctor I'd not heard of viepax but online it is referred to as venlafaxine hydrochloride, slow release. Generic drugs are supposedly exactly the same as the name brands, only they can't be manufactured until a certain time after the initial rights belonging to the creators have expired. Sertraline Zoloft Side Effects Weight Gain, Dosage &. viagra monograph Zoloft; INN sertraline Sertraline - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol.
     
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