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Levofloxacin solution is administered by slow intravenous infusion once or twice daily. The dosage depends in the type and severity of the infection and the susceptibility of the presumed causative pathogen. Treatment with levofloxacin after the initial use of the intravenous preparation may be completed with an appropriate oral levofloxacin presentation, in accordance with it's SPC, and as considered appropriate for the individual patient. Given the bioequivalence of the parenteral and oral forms, the same dosage can be used. Posology The following dose recommendations can be given for levofloxacin: Dosage in patients with normal renal function (creatinine clearance Treatment duration includes intravenous plus oral treatment. The time to switch from intravenous to oral treatment depends on the clinical situation, but is normally 2 to 4 days. 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