Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Hydroxychloroquine plaque psoriasis Hydroxychloroquine vs truvada Plaquenil thrombocytopenia Success with plaquenil If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. Photosensitivity is a skin reaction i.e. rash that occurs after exposure to ultraviolet UV radiation from the sun or an artificial light source. Photosensitivity can be caused by various agents, including drugs, perfume, cosmetics, and even the sunscreen that is meant to protect your skin. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Plaquenil and sun rash Common and Rare Side Effects for Plaquenil Oral, Photosensitivity Reaction With Certain Medications Does plaquenilSide affectss of plaquenilDoes chloroquine interact with vitaminsHydroxychloroquine eye floaterOct test for plaquenil Re Plaquenil and Sun Exposure Reply #13 on June 12, 2011, AM After a long dark winter of seeing no sun, I finally went into the sun for an hour, early in the morning, and over the next day, developed a red raised rash on all exposed parts, a rash that lasted for several weeks. Plaquenil and Sun Exposure - Sjogren's World. Plaquenil Side Effects Common, Severe, Long Term -. UV exposure What you need to know Lupus Foundation of America. Skin rash – Plaquenil can rarely cause a rash. Patients who experience this rare side effect should stop taking this medicine and contact their doctor. Headaches – Plaquenil can rarely cause a headache. Sun Sensitivity – Plaquenil can sometimes make the skin more sensitive to the sun. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or; hair loss. I have hip and back pain, and rashes with sun exposure also. Avoiding the sun is important. It took me awhile to understand that it was causing flare symptoms as well as rash. Sun block is essential - even for a dash to the car, etc. Plaquenil is also sometimes used for RA.