The most common side effect associated with its use is retinal toxicity, which may be irreversible. Therefore, it is pertinent to know the findings, risk factors, and screening tests necessary to prevent retinal damage. Hydroxychloroquine and peripheral neuropathy Plaquenil stop hair loss How to take chloroquine for malaria prophylaxis The changes are most often permanent, but in some cases, vision has improved. Most rheumatologists recommend patients undergo a baseline eye examination prior to starting Plaquenil and be re-examined in the future depending on their risk for developing the condition. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. During the first five years of use, the rate of toxicity was found to be 0.7%, rising significantly to more than 1% after five to seven years of use. The prevalence of retinal toxicity has varied among different studies. Visual field changes with plaquenil Hydroxychloroquine Plaquenil Toxicity and Recommendations., Hydroxychloroquine Plaquenil Toxicity and. Plaquenil side effects fluid retention Nov 01, 2015 In many cases, the diagnosis of HCQ retinal toxicity was delayed when visual field tests were dismissed as “nonspecific.” Therefore, an abnormal visual field should first be repeated. If consistent changes are confirmed, one or more of the objective tests discussed below should be performed. Retinal Physician - Hydroxychloroquine Maculopathy An Update.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Visual Fields and Plaquenil Medical Billing and Coding.. Ones to check for any changes. You will continue to be screened every year until you stop taking hydroxychloroquine. Possible retinopathy If there is an abnormality found in any one test it means there is a possibility of there being signs of hydroxychloroquine retinopathy. If the abnormal test is the visual field test, you may be Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Apr 20, 2011 Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area.