I have been on plaquenil for about 10 weeks now without much success. I have had the sickness to my stomach and not felt like me including exhausted but it's not as bad as I feared. My hair is coming out slightly Not in clumps are anything, just a little here or there. My doctor said if I don't feel better in a few more weeks, we could switch my medicine. Really though in order not to have worse things happen it is what we have to do. I switched back to cymbalta three days ago and have experienced huge relief. Chloroquine phosphate tablets ip 250 Plaquenil generic brand Chloroquine pregnancy category Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice. If you can't take Plaquenil. deleted_user 06/18/2012. I've read on these forums that a lot of people take methotrexate. I have been on the plaquinel for a year now and it's been working for me, but you are definitely not alone finding plaquinel doesn't do the job for you. And prednisone is poisonous for me--major high blood pressure and. Methotrexate and plaquenil. now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. i am still in so much pain everyday and hoping for some relieve soon. Vitamin B-12 might help with the hair, ask your doctor about that, well wishes to you and I hope the mtx can help you....((((((((((((((((((((((((((((((((((((((((((((((Jeanneac)))))))))))))))))))))))))))))))))))))))))healing hugz and well wishes and keep us posted on how your doing... Had headaches with the plaquenil so went to the sulfar and predisone. (like i did friday) Take care of yourself and big(((HUGS))) on your journey. He said it would be one that they would have to more closely monitor me on with some blood tests. I was thinking it was methotrexate but I do not want my hair to fall out. It might be coincidence but since on the plaquenil, I have noticed a growth spurt of hair especially at the hairline. Plaquenil made me sick, so I can't take it either, but there are other medicine out there,the doctor's will get you on something that'll help, keep hope..wishes to you and try the methotrexate,to see if it can help... I know it is scary but anything to stop the pain and misfunction of not being able to use my hands or move my knees or not have my ankles cave out and fall. I suspected that I had fibromyalgia on top of the inflammation. I am so relieved but hope I don't start having bad side effects from it like I did before with a very dry mouth and gritting my teeth at night. Can you take methotrexate without plaquenil Rheumatoid Arthritis Treatment Options Johns Hopkins., If you can't take Plaquenil DailyStrength Generalized granuloma annulare hydroxychloroquineTussin dm and hydroxychloroquine interactionSigns of retinal damage from plaquenilLdn and plaquenil WebMD provides information about which foods to avoid while taking Plaquenil Oral. Foods to Avoid When Taking Plaquenil Oral. Methotrexate and plaquenil -. Taking Plaquenil for Rheumatoid Arthritis. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Taking both drugs at the same time can increase the risk of damage. Can You Take Ibuprofen and Plaquenil Together? Plaquenil has been used safely in combination with salicylates aspirin, non-steroidal anti-inflammatory drugs such as ibuprofen, methotrexate and corticosteroids. What Should You Tell Your Doctor Before Taking Plaquenil? Methotrexate can lower the risk that patients start producing anti-drug antibodies, which are a particular problem when treating patient with monoclonal antibody drugs. Without methotrexate taken in combination with another drug, patients are less likely to respond well over time. Jeffrey R. Curtis, M. D.