Chloroquine skin pigmentation

Discussion in 'Hydroxychloroquine Sulfate 200 Mg' started by Booty Pie, 12-Mar-2020.

  1. seo-start XenForo Moderator

    Chloroquine skin pigmentation


    In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent.

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    Desorption of chloroquine and hydroxychloroquine from Sepia melanin. Initially 5 mg of melanin was saturated by equilibration with 5 mL of 1.9 mmol/L chloroquine prepared in 20 mM potassium phosphate buffer at pH 7.4 for 2 h. The samples were then centrifuged at 477 × g for 4 min and the supernatant removed. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. The skin lesions were macular or patchy, some well and others poorly demarcated, with a hyperpigmentation of gray to black discoloration, generally annular, but some with irregular morphology. They were flat without induration or scaling. A diagnosis of HCQ-associated hyperpigmentation was made, and HCQ was discontinued.

    Authors: Dr Anes Yang, Clinical Researcher, Department of Dermatology, St George Hospital, University of New South Wales, Sydney, NSW, Australia; Dr Monisha Gupta, Senior Staff Specialist, Department of Dermatology, Liverpool Hospital, Sydney, NSW, Australia. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended.

    Chloroquine skin pigmentation

    Discolored Skin Patches Pictures, Causes, and Treatments, Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs

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  4. Skin itchiness, skin color changes, hair loss, and skin rashes. Chloroquine-induced itching is very common among black Africans 70%, but much less common in other races. It increases with age, and is so severe as to stop compliance with drug therapy.

    • Chloroquine - Wikipedia.
    • Hydroxychloroquine-induced Hyperpigmentation of the Skin..
    • Drug-Induced Pigmentation Background, Pathophysiology, Etiology.

    Changes of the skin and mucus membrane during the course of chloroquine therapy for connective tissue disorders. These female patients developed hyper pigmentation of the skin, largely on the exposed parts Chloroquine, hydrocychloroquine, amodiaquine and quinacrine are all example of antimalarials which can cause skin pigmentation. What does the skin pigmentation look like? Usually, when you start taking antimalarials, the areas of skin pigmentation which they can cause are small and oval in shape. As you take more antimalarials, the skin pigmentation will usually develop into large patches of discolouration. Jul 30, 2019 Several cases of hypopigmentation of the skin have been reported. Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy.

     
  5. Anuta XenForo Moderator

    This is not a list of all drugs or health problems that interact with chloroquine. Chloroquine Indications, Side Effects, Warnings - Effect of chloroquine on feline infectious peritonitis virus. Chloroquine phosphate C18H32ClN3O8P2 - PubChem
     
  6. Jayson Guest

    Adelgazar no es una tarea fácil y más cuando nos encanta la comida poco saludable y no nos gusta mucho hacer ejercicios, sin embargo, últimamente vemos como muchas personas han tomado conciencia de lo beneficioso que es para nuestra salud, llevar hábitos de vida saludables, que además de ayudarnos a mantener nuestro peso ideal, también nos haga lucir ese cuerpo que tanto deseamos. Para que sirve hydroxychlor - Salud - Ejercicios para bajar de peso y cuántas calorías se. Beber agua para bajar de peso ¿Mito o realidad? - AARP
     
  7. maslvehduard XenForo Moderator

    Plaquenil hydroxychloroquine – New Warnings Discontinuation of Plaquenil may prevent life-threatening complications. — Plaquenil prolongs the QT interval. Ventricular arrhythmias and torsades de pointes have been reported in patients taking Plaquenil. Plaquenil should not be administered with other drugs that have the potential to prolong the QT interval.

    Plaquenil Concordia Pharmaceuticals Inc. FDA Package Insert