One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine undifferentiated connective tissue disease Plaquenil apteka Plaquenil and skin changes Side affectss of plaquenil It has become fairly common practice for most rheumatologists to recommend that patients being treated with hydroxychloroquine be seen for formal visual field evaluation once or twice a year to monitor for retinal toxicity. The previous AAO guideline recommended screening every 12 months. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil toxicity monitored 24-2 or 10-2 Plaquenil Hydroxychloroquine Sulfate - Sanofi, Plaquenil Uses, Dosage & Side Effects - Long term effects of plaquenilVisual defects hydroxychloroquineCan you take birth control with plaquenil A multitude of tests are needed to detect the earliest possible signs of hydroxychloroquine toxicity, according to Andrew A. Moshfeghi, MD, MBA. field 24-2 in addition to a 10-2 is necessary. Despite Plaquenil dosing recommendations, retinal toxicity remains. Protecting your eyesight when taking Plaquenil Lupus.. Plaquenil Guidelines Point Out New Risks, New Presentation.. SITA testing with pattern deviation plots is recommended. Wider test patterns 24-2 or 30-2 are needed for Asian patients due to the possibility of extra-macular manifestations of toxicity. Large test patterns only test 4 points centrally. There was no mention of testing both 10-2 and large test patterns in the AAO guidelines for Asian patients. The 10-2 red test has been recommended in the past as the testing strategy of choice for HCQ toxicity due to its sensitivity. 1,5 Easterbrook 1 reported the 10-2 red test to be 91% sensitive for detection of HCQ toxicity. However, he also reported a low specificity of 57% for this test. Although it is considered rare, retinal toxicity from the intake of Plaquenil can be irreversible even if the drug is discontinued 2, 3. What is Plaquenil Toxicity? The toxicity resulting from the intake of Plaquenil is due to its affinity for melanin-containing structures in the body.