In people with sarcoidosis, abnormal masses or nodules (called granulomas) consisting of inflamed tissues form in certain organs of the body. These granulomas may alter the normal structure and possibly the function of the affected organ(s). Plaquenil reduction Hydroxychloroquine dose dialysis Malarone doxycycline chloroquine ou mefloquine I was also diagnosed in August 2013 and also can't take prednisone. I was on plaquenil for 4 - 5 months and my lungs got worse, doc said plaquenil wasn't strong enough. I'm now on 10 mg/wk methotrexate, and sarcoidosis seems to be better. Hydroxychloroquine and chloroquine These oral antimalarial drugs have been used to treat sarcoidosis of the skin, lungs, and nervous system. They are used to treat the hypercalcemia seen with sarcoidosis. Patients on these drugs need occasional monitoring of their eyes by an ophthalmologist. Aug 03, 2009 Side-effects were mainly limited to the high dose treatment phase. The authors conclude that chloroquine should be considered in chronic pulmonary sarcoidosis; in practice, hydroxychloroquine is preferred because it has lower ocular toxicity. Most patients initially complain of a persistent dry cough, fatigue, and shortness of breath. The symptoms of sarcoidosis can vary greatly, depending on which organs are involved. Plaquenil pulmonary sarcoidosis Experience of hydroxychloroquine in the treatment of., Sarcoidosis Treatment - Cleveland Clinic Metabolic fate of chloroquineReticulocytes chloroquine treatment p62Plaquenil and imuran heat and sun side effectsMetabolic encephalopathy plaquenilPlaquenil testing optometry Pulmonary sarcoidosis is an inflammatory condition where abnormal tissue forms in the lungs. Often the lymph nodes within the chest cavity are also affected. This abnormal tissue is known as a granuloma and is the type of tissue that arises when the body tries to wall off an infection. Pulmonary Sarcoidosis Lungs Causes, Symptoms, Treatment.. Management strategies for pulmonary sarcoidosis. Sarcoidosis - Wikipedia. Jul 21, 2017 The stages of pulmonary sarcoidosis should also not be mistaken to indicate the progression of the disease- the “stages” are simply a way doctors interpret the results of scans of the chest- read on for more information. If you are looking for information on severe and chronic sarcoidosis regardless of the organ that is affected, refer to. Sarcoidosis is an inflammatory disorder resulting in noncaseating granulomas in one or more organs and tissues; etiology is unknown. The lungs and lymphatic system are most often affected, but sarcoidosis may affect any organ. Pulmonary symptoms range from none to cough, exertional dyspnea and, rarely, lung or other organ failure. Chloroquine CQ can be an effective treatment for lung sarcoidosis with few side effects, but has not been accepted as standard therapy. We investigated the benefits of prolonged CQ therapy in 23 symptomatic patients with biopsy-proven pulmonary sarcoidosis duration, ⩾ 2 yr.