Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine 250 mg tablets Hydroxychloroquine retinopathy dose Plaquenil elevated liver enzymes At first, 13 mg per kg of body weight taken as a single dose. Then, 6.5 mg per kg of body weight taken 6 hours, 24 hours, and 48 hours after the first dose. However, dose is usually not more than 800 mg for the first dose and not more than 400 mg for the next doses. For treatment of arthritis Adults—At first. Fourth dose 5 mg base/kg 24 hours after third dose Each dose should be taken with a meal or a glass of milk. Concomitant therapy with an 8-aminoquinoline drug is necessary for the radical cure of vivax and malariae malaria. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Dosage of plaquenil Hydroxychloroquine Dosage Guide with Precautions -, Hydroxychloroquine Uses, Dosage & Side Effects - Cpt code plaquenil therapySaposin b binds chloroquinePlaquenil and hair dyeChloroquine phosphate 250 mg day Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Despite Plaquenil dosing recommendations, retinal toxicity remains. Treatment of Uncomplicated Malaria Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base. Why Use. Use in an outpatient setting for adult patients taking hydroxychloroquine Plaquenil. The current American Academy of Ophthalmology AAO guidelines, published in 2016, recommend a maximum daily hydroxychloroquine dose of ≤5.0 mg/kg of real weight. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams.