He reported a history of tick bite and rash in 2002. The knee pain and other symptoms rapidly improved over the next two weeks. He received a short course of antibiotics at that time. After two weeks he reported that the antibiotics were causing nightmares and insomnia. Then one week later he complained of confusion and unsteadiness. Plaquenil 40 mg Royal college of ophthalmologists hydroxychloroquine Plaquenil hives treatment MATERIAL/METHODS 235 patients with a multi-symptom complex typical of chronic Lyme disease, ie fatigue, musculoskeletal pain, and neurocognitive dysfunction and with serologic reactivity against B.burgdorferi were treated with a macrolide antibiotic eg clarithromycin and hydroxychloroquine. My daughter’s LLMD wants to add a Plaquenil pulse to my daughter’s protocol and thinks it might boost her babesia treatment. I’ve read mixed reviews on this drug and it seems that most lyme drs use it to increase the efficacy of certain Lyme treatments but not as much for babesia. Dec 16, 2008 A 70 year old male patient was diagnosed with Lyme disease 6 or 7 months ago. He reported a history of tick bite and rash in 2002. He received a short course of antibiotics at that time. When I saw him initially he complained of knee pain and swelling, fatigue, generalized arthralgia joint pain, numbness and tingling and an irregular heart beat. He continued to improve rapidly once more with a cessation of neurocognitive symptoms. When I saw him initially he complained of knee pain and swelling, fatigue, generalized arthralgia (joint pain), numbness and tingling and an irregular heart beat. I diagnosed a "brain Herx." I added Plaquenil back, as well as Welchol, presumptively to remove "neurotoxins." I also reduced the dose of Amoxicillin and Minocin. Plaquenil lyme disease treatment How effective is Plaquenil for Lyme disease by duration., Plaquenil Plaquenil sarcoidosis treatmentNumber needed to treat hydroxychloroquine Plaquenil is often perceived as an anti-arthritis drug used to treat connective tissue disorders. What it does is make the body more alkaline. My doc explained that he prescribes it with Biaxin Clarithromycin-an intracellular abx because by making the body more alkaline, the Biaxin can more easily penetrate the body's cells, which makes it up to 40% more effective. Plaquenil for treatment - Lyme Disease - MedHelp. LymeMD Plaquenil alone?. What Exactly Is Hydroxychloroquine, The Drug That Is Being.. Lyme arthritis for 40 months with continuous disease activity that resolved in conjunction with the adminis- tration of hydroxychloroquine. Case Report. The patient is a 41-year-old white man who was well until August 1976 when he suffered a tick or insect bite on the lateral aspect of his right knee. A skin lesion developed that was described as Lori, I'm not medically trained, but here's what I find on the internet for your consideration Plaquenil is a drug used to treat malaria and also in autoimmune conditions such as lupus and rheumatoid arthritis. The references I have found as to using it in Lyme treatment combine Plaquenil with another medication at the same time. Hi, I have lyme disease and have frequently been on plaquenil only in the summer as stronger drugs are used when I'm not in the sun and I've yet to experience this. But I do know that it is often used to prevent and treat malaria and that many drugs that deal with such things have a tendency to cause some crazy dreams.