Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. What is plaquenil use for Deae dextran chloroquine method Plaquenil and antiplatelet drugs Chloroquine diphosphate salt C6628 - Product Information Sheet Author Sigma-Aldrich Corp. Subject This product is a member of the quinoline family with multiple applications. It was originally used as an antimalarial compound. Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase. Pharmacokinetics of chloroquine diphosphate in the dog. Aderounmu AF, Fleckenstein L. Chloroquine diphosphate was administered i.v. and orally to seven male beagle dogs. Approximately 2 mg/kg was administered i.v. and 4 weeks later a single 150-mg tablet dose was administered orally. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine diphosphate and phosphate Chloroquine diphosphate salt powder or crystals, 98.5-101., Chloroquine phosphate C18H32ClN3O8P2 - PubChem Plaquenil reportAcute chloroquine toxicityPlaquenil sun sensitivity tinglingSub for plaquenil A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Chloroquine Indications, Side Effects, Warnings -. Pharmacokinetics of chloroquine diphosphate in the dog.. Chloroquine phosphate REEF2REEF Saltwater and Reef.. Structure, properties, spectra, suppliers and links for Chloroquine diphosphate, 50-63-5, Chloroquine Phosphate. Sasaki et al 2010 Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 10 370 PMID 20630104. If you know of a relevant reference for Chloroquine diphosphate, please let us know. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat.