Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine 250mg Chloroquine maculopathy dose Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the. Annual screening may be commenced before 5 years of treatment if additional risk factors for retinal toxicity exist, such as concomitant tamoxifen therapy, impaired renal function eGFR less than 60 mL/minute/1.73 m 2 or high-dose therapy greater than 5 mg/kg/day of hydroxychloroquine sulfate. Immunosuppressive effects of hydroxychloroquine and artemisinin combination therapy via the nuclear factor-κB signaling pathway in lupus nephritis mice Ning Liang, 1, 2, * Yanchun Zhong, 1, * Jie Zhou, 1 Bihao Liu, 1 Ruirui Lu, 1 Yezhi Guan, 3 Qi Wang, 4 Chunlin Liang, 1 Yu He, 1 Yuan Zhou, 1 Jianping Song, 3 and Jiuyao Zhou 1 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Is hydroxychloroquine sulfate an immunosuppressant Hydroxychloroquine SULFATE -, HYDROXYCHLOROQUINE SULFATE Drug BNF content published. Diamondback chloroquine phosphatePlaquenil for sarcoidosisPlaquenil rosacea It is a weak immunosuppressant that does not require regular blood monitoring and is usually used in conjunction with sunscreens and topical steroids. Side-effects include corneal deposits and retinal toxicity. These side-effects are less with hydroxychloroquine than with chloroquine. Hydroxychloroquine - an overview ScienceDirect Topics. Immunosuppressive effects of hydroxychloroquine and artemisinin.. Hydroxychloroquine Oral Route Description and Brand Names - Mayo Clinic. The study is based on hydroxychloroquine sulfate the active ingredients of Plaquenil and Plaquenil the brand name. Other drugs that have the same active ingredients e.g. generic drugs are not considered. Dosage of drugs is not considered in the study. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Summary Immunodeficiency disorders is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years, also take medication Methotrexate, and have Hypersensitivity.