Malaria: Treatment of uncomplicated malaria caused by susceptible strains of Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium falciparum; prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Limitations of use: Hydroxychloroquine is not effective against chloroquine- or hydroxychloroquine-resistant malaria strains of Plasmodium species; not recommended for treatment of complicated malaria, malaria prophylaxis in regions with chloroquine resistance, or treatment when the Plasmodium species has not been identified; hydroxychloroquine does not prevent relapses of P. ovale infections because it is not effective against the hypnozoite forms of these parasites. Hydroxychloroquine generic brands Plaquenil not working Is hydroxychloroquine a hydrocodone Lichen Planopilaris LPP is a form of scarring alopecia and is a rare inflammatory condition that results in patchy permanent hair loss on the crown and vertex. It destroys the hair follicle and replaces it with scarring. Symptoms can include an intensely itchy scalp and scalp tenderness. LPP is considered a follicular form of Lichen Planus. Plaquenil has been used because of its benefit in patients with discoid lupus erythematosus, another lymphocyte-mediated scarring alopecia. Isotretinoin, dapsone, and thalidomide have all been tried. The biologics are also being tried for LPP. In my experience, LPP waxes and wanes over time, probably without regard to treatment. Published evidence says that it is mediated by T-lymphocytes. Plaquenil is an anti-inflammatory drug approved by the FDA for malaria, lupus erythematosus, and rheumatoid arthritis. It has an effect on T-lymphocyte mediated inflammation, making it a logical choice for a treatment trail for alopecia areata. Data from case reports and retrospective and open-label studies support the use of hydroxychloroquine in the treatment of cutaneous manifestations of dermatomyositis . Rheumatoid arthritis: Treatment of acute and chronic rheumatoid arthritis in adults. Plaquenil treatment for alopecia Lichen planopilaris Genetic and Rare Diseases., Lichen Planopilaris Treatment Dermatology Education Test done before plaquenilPlaquenil and surgery riskCan you breastfeed while on plaquenilEye problems on hydroxychloroquine Medical Care. Few large, randomized, blinded, controlled studies are available. Most treatments are considered off label. Stimulating hair growth using options often considered for nonscarring alopecia has been attempted with mixed results, and these include finasteride, minoxidil topically, and bimatoprost injections. Scarring Alopecia Treatment & Management Medical Care.. Plaquenil for Alopecia Areata, Alopecia Totalis - Full.. I have been prescribed hydroxychloroquine to reduce my.. Hydroxychloroquine could be beneficial as a treatment option for children with alopecia areata AA, according to Duri Yun, MD, of the University of Chicago Medicine, and associates. Treatment of central centrifugal cicatricial alopecia. The goal of therapy is to halt progression of disease and prevent further hair loss. In areas where the hair follicle has been replaced with fibrosis, regrowth is not possible. As the exact cause is not known, targeted therapy for CCCA is not available. Hydroxychloroquine is significantly effective, after 6 and 12 months of treatment, in decreasing symptoms and signs in lichen planopilaris and frontal fibrosing alopecia. More patients respond to hydroxychloroquine after 12 months than 6 months. A standardized flow chart is essential to track symptoms and signs and facilitate treatment decisions.