An audit of 100 patients seen at any of nine Canadian rheumatology clinics during early 2016 showed that 30% of patients were not on appropriate weight-based hydroxychloroquine dosages, and 13% of patients on the drug had not received a baseline retinal assessment during their first year of treatment, “We are significantly below the standard of care for appropriately dosing and screening” patients treated with hydroxychloroquine (Plaquenil), concluded Dr. Koppikar, an internal medicine physician at Queens University in Kingston, Ont. Opthalmologic complication of hydroxychloroquine Chloroquine phosphate price Quinoric vs plaquenil The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. Plaquenil has less systemic side. The recommended dose of hydroxychloroquine Plaquenil in adults is 400 mg on exactly the same day of each week. The recommended weekly suppressive dose of hydroxychloroquine Plaquenil in children 6 years of age and older is 5 mg base/kg. This dose should not exceed the adult dose reg ardless of body weight. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3 The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Although his study did not examine reasons for the compliance shortfall, Dr. HCQ comes only as 200-mg tablets, and prescribing intermediate dosages can be a challenge (although veteran clinicians know that a safe and easy way to dial down a dosage is to have the patient periodically skip a dose). In a second recently reported study, researchers from the Chicago area documented that roughly half of the 554 rheumatology patients on hydroxychloroquine (HCQ) in a regional health system and seen by an ophthalmologist during 2009-2016 received an excessive dosage of the drug (). Recommended dosage of plaquenil Plaquenil hydroxychloroquine sulfate dose, indications., Plaquenil - Side Effects, Uses, Dosage, Overdose. Hydroxychloroquine 200 mg nombre comercialHydroxychloroquine and nerve damageHydroxychloroquine test for eyes Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. New Plaquenil Guidelines. Hydroxychloroquine dosage recommendations often ignored.. The recommended Plaquenil dosage for malaria prevention is 400 mg once weekly, starting two weeks before the anticipated exposure. The usual starting dosage for treating lupus is 400 mg once or twice a day, and the recommended starting dose for the treatment of rheumatoid arthritis is 400 to 600 mg daily. Jun 30, 2015 The recommended dose of hydroxychloroquine Plaquenil in adults is 400 mg on exactly the same day of each week. The recommended weekly suppressive dose of hydroxychloroquine Plaquenil in children 6 years of age and older is 5 mg base/kg. This dose should not exceed the adult dose reg ardless of body weight. This apparently resulted in overdosing of thin patients. Thus, the patient’s real weight is now recommended as the basis for calculating the daily dose per weight in kg. Doses ≥ 5 mg/kg/day real weight of hydroxychloroquine 2.3 mg/kg/day of chloroquine are associated with higher risk of toxicity.