Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Is there a difference between plaquenil and hydroxychloroquine Plaquenil what does it do Plaquenil purchase online More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow. By Connie Rifenburg June 3, 2015 at pm. Ang, I had hair loss pretty severe when I first started on Prednisone, Plaquenil, and Methotrexate. I guess it may depend on the dosage, and hopefully your hair loss will stop as mine did after a few months. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and prednisone interaction Prednisone/Plaquenil question -, Prednisone and Plaquenil question" Lupus Community. Chloroquine side effects medscapePlaquenil cheapestChloroquine 500mg tabHow long can you stay on plaquenilPlaquenil safer than fluoroquinolones How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil and Prednisone. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Re Plaquenil - Better Than Prednisone? Have been taking Plaquenil for over a year now and it has definitely made a huge difference in my quality of life. When I first went to my Rhuemy and found out what was wrong, I was so sick I could barely function with fatigue, joint and muscle aches just to name a few. Side effects of prednisone that are different from Plaquenil include acne, thinning skin, weight gain, restlessness, and trouble sleeping. Both Plaquenil and prednisone may interact with antibiotics, tuberculosis medications, nonsteroidal anti- inflammatory drugs NSAIDs, HIV / AIDS medications, estrogens including oral contraceptives or hormone replacement therapy, or seizure medications. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in.