Long-term progression of hydroxychloroquine retinopathy off the drug marmor

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  1. shurupp Moderator

    Long-term progression of hydroxychloroquine retinopathy off the drug marmor


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Mar 10, 2017 Although drug cessation, partly due to long half-life of the drug, does not always arrest progression of toxicity, it can limit the extent of structural and functional deficits and reduce the risk. Our prevalence data apply to the overall population of long-term hydroxychloroquine users, and risk rises markedly after 10 years of use. However, in rheumatologic practices, many patients benefit from the use of the drug for much longer periods, and it is important to know the annual risk as they stay on the drug regimen. Progression of Hydroxychloroquine Toxic Effects After Drug Therapy Cessation New Evidence From Multimodal Imaging. and long-term follow-up of patients with hydroxychloroquine retinopathy.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Long-term progression of hydroxychloroquine retinopathy off the drug marmor

    AMERICAN COLLEGE OF RHEUMATOLOGY, The Risk of Toxic Retinopathy in Patients on Long-term.

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  4. Aug 30, 2011 The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. JAMA Ophthalmol 2014;153–60. Wolfe F, Marmor MF Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus.

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    One study identified the utility of monitoring tests to detect progression in patients diagnosed with hydroxychloroquine retinopathy 13 to 40 months after the drug was discontinued. Concomitant renal or liver disease because the drug is cleared by both routes underlying retinal disease or maculopathy ; age greater than 60 years. Monitoring Guidelines. Guidelines on screening for retinopathy associated with hydroxychloroquine toxicity were initially published by the Academy in 2002. Oct 16, 2014 Hydroxychloroquine is often prescribed as long-term therapy for many dermatologic indications, and it may have broader benefits e.g. preventing or improving thrombophilia associated with lupus erythematosus, neonatal lupus erythematosus, diabetes in rheumatoid arthritis and other connective tissue diseases, and as adjunctive therapy in some cancers.

     
  5. else27 User

    Someone who has a sulfa allergy can react to some medications that contain sulfa. Sulfa Allergy Symptoms, Causes, Diagnosis, and Treatment Can you take Hydroxychloroquine if you are allergic to sulfa. Are chloroquine and sulfa related - Answers on HealthTap
     
  6. shurik44 Well-Known Member

    The Safety of Elective Surgery with Concurrent Use of. Kumar et al. 18 literature analysis consisting of 84 articles regarding perioperative management of patients with IBD concluded that continued use of mercaptopurine does not negatively influence surgical outcomes or increase morbidity following elective surgery.

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