Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil history Chloroquine class of drug If chloroquine should indeed inhibit the biosynthesis of sialic acid, this effect could explain not only the effects of chloroquine on HIV and SARS coronavirus sialic acid moieties are present in HIV-1 glycoproteins and SARS coronavirus receptor ACE2, but also the in-vitro effects on orthomyxoviruses which use sialic acid moieties as receptors Drug Safety in Lactation. Information on this subject has been updated. Read the most recent information. Prescriber Update 21 10- Sharon Gardiner, Drug Information Pharmacist, Christchurch Hospital and Evan Begg, Clinical Pharmacologist, Christchurch School of Medicine. Many mothers are required to use drugs during breastfeeding. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine in lactation Chloroquine use while Breastfeeding, Drug Safety in Lactation Information on plaquenilHydroxychloroquine skin discolorationChloroquine trade name in egypt Safety in Lactation Antimalarials Published 20th May 2012, updated 19th April 2016. Wherever possible, travelling into endemic countries should be delayed until after the lactation period. Safety in Lactation Antimalarials – SPS - Specialist.. What is Chloroquine Phosphate? - GoodRx. Chloroquine - Uses, Dosage, Side Effects, Composition.. Can I take Chloroquine while breastfeeding? Very small amounts of chloroquine are excreted in breast milk; when given once weekly, the amount of drug is not sufficient to harm the infant nor is the quantity sufficient to protect the child from malaria. Chloroquine is a 9-aminoquinoline that has been known since 1934. Specifically synthesised to be used as an antimalarial agent, chloroquine was subsequently shown to have immunomodulatory properties that have encouraged its application in the treatment of autoimmune diseases such as rheumatoid arthritis. Chloroquine has not been shown to have any harmful effects on the fetus when used for malarial prophylaxis. Small amounts of chloroquine are excreted in the breast milk of lactating women. However, because this drug can be safely prescribed to infants, the effects are not harmful.