Ongoing monitoring of blood counts, liver and kidney function is also required. Prescribed for Acute Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Rheumatoid Arthritis, Psoriatic Arthritis, Solid Tumors, Small Cell Lung Cancer, Systemic Sclerosis, Neoplastic Diseases, Trophoblastic Disease, Osteosarcoma, Non-Small Cell Lung Cancer, Non-Hodgkin's Lymphoma, Psoriasis, Mycosis Fungoides, Dermatomyositis, Breast Cancer, Choriocarcinoma, Meningeal Leukemia, Graft-versus-host disease, Head and Neck Cancer, Juvenile Idiopathic Arthritis, Lymphoma. Hydroxychloroquine nursing considerations How effective is plaquenil for rheumatoid arthritis The effects of methotrexate and hydroxychloroquine combination therapy vs. MTX–HCQ combination therapy—together with a DAS28-based treat-to-target treatment. Learn about drug interactions between hydroxychloroquine oral and methotrexate sodium oral and use the RxList drug interaction checker to check drug combinations. Sorry to hear that you are having a lot of pain with your RA. I have lupus which mainly affects my joints and skin. I have been taking hydroxychloroquine which is the generic of plaquenil for the past three years. My rheumy recently added Imuran instead of methotrexate. Plaquenil hydroxychloroquine takes up to 3 months to begin working. " Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. May also be prescribed off label for Bladder Cancer, Acute Nonlymphocytic Leukemia, Soft Tissue Sarcoma, Scleroderma, Pityriasis rubra pilaris, Pemphigus, Pemphigoid, Pancreatic Cancer, Ovarian Cancer, Mantle Cell Lymphoma, Brain Tumor, Bullous Pemphigoid, Cervical Cancer, Cogan's Syndrome, Colorectal Cancer, Ectopic Pregnancy, Eczema, Esophageal Carcinoma, Gastric Cancer, Hodgkin's Lymphoma, Uveitis. Taking methotrexate and plaquenil together Methotrexate and plaquenil - @Kristinsaba1988 - Scleroderma., Hydroxychloroquine oral and methotrexate sodium oral Drug. Plaquenil and menstrual cyclePlaquenil 200 mg canada price Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Methotrexate vs Plaquenil Comparison -. Which would you pick and why? - Plaquenil or Methotrexate. . Drug interactions are reported among people who take Plaquenil and Naproxen together. This study is created by eHealthMe based on reports of 1,166 people who take Plaquenil and Naproxen from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in.