At first it seemed like it helped now I feel the same as before I started taking the medicine other than the fact that none of my clothes fit and there is a lot more of me to carry around. Anyone know if I quit taking it if the weight will fall back off I started Hydroxychloroquine 2 weeks ago. One week in and I thought this may just work, except for the ‘extra itchiness’ I seemed to get every night. Plaquenil osteoarthritis treatment Plaquenil and hypoglycemia Withdrawal from plaquenil Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. I was diagnosed with systemic erythematosus lupus SLE in January of 2013 at the age of 44 yes old. I was referred to a Rheumy who put me on daily dose of 200 mg of hydroxychloroquine sulfate. I was prescribed this drug to ease my ra disease, I was taking 400mg per day which was to last for 3 months then reduced to 200mg. Right before I hit the two week mark, I woke up with my heart racing and continued feeling my heart flutter all day and I just felt week and tired. After msging Rheum, decided to stop taking meds to see how I feel and continue with the AIP to handle symptoms and try to work at ‘healing from inside out! Time will tell and I’m eager to see how much the AIP is helping once odd meds. Sle on plaquenil Systemic lupus erythematosus - Wikipedia, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center How to taper plaquenil 300mg daily Birmingham, AL - Starting the antimalarial drug hydroxychloroquine HCQ Plaquenil early on in the disease process may help prevent damage accrual in patients with systemic lupus erythematosus. Hydroxychloroquine in SLE. Hydroxychloroquine Reviews Everyday Health. Plaquenil. A medication for Lupus. In patients with systemic lupus erythematosus SLE, hydroxychloroquine prevents disease flares and damage accrual and facilitates the response to mycophenolate mofetil in those with renal involvement. A study was undertaken to determine whether hydroxychloroquine also exerts a protective effect on survival. SLE Clinical Presentation. SLE disease activity can be defined as the sum of all abnormalities due to ongoing immune inflammatory pathways involved in SLE. 1 Disease activity can be assessed by clinical features eg, arthritis and rash, serologic features eg, decreased complement and increased anti-dsDNA and laboratory features eg, urinalysis and WBC. 2,3 Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year.