You get more ACE2 receptors though if you smoke or have diabetes or if you lige a place with a lot of air pollution.https://gov/pmc/articles/PMC2911869/https://gov/pmc/articles/PMC1287568/I'm not a doctor so this is to be taken as medical advise or a reason to skip any precautions. I'm also certain the scientists will learn much more and perhaps change their views later. Half life of hydroxychloroquine sulfate Are hydroxyzine and plaquenil the same thing Chloroquine toxicity of retina Plaquenil didn't seem to work for me when I tried it. There are of course other medications out there that perhaps Gareth would do better on. I was put on methotrexate instead, and didn't really notice much of a change, from what I could tell. Let me know what you want to learn from me . That's a strong plus for Plaquenil since many other drugs that work on the immune system also weaken it and can thereby increase the risk for. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. I only write it, because reading this made me feel less nervous and it might help others too. You should also note that a slighter risk does not equate to immunity and that other health factors may make you more or less susceptible. Plaquenil did not work for me User Reviews for Hydroxychloroquine to treat. -, Plaquenil Hydroxychloroquine for use in Autoimmune disease. Side. Hydroxychloroquine mechanism of action sle For me it did not start so quickly. You need to build a therapeutic level for any real benefit. Sometimes that is how Sjogren's works. Symptoms seem to disappear for a few days and reappear. Plaquenil eventually helped my joint pain. The continued fatigue and other symptoms are related to my mctd so I am not the perfect judge for this. How does Plaquenil work?. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil is being used to treat Covid 19 lupus. Haven't taken this. Just wanted to read some feedback. I was on methotrexate, but stopped, because it gave me chills, fatigue and shortness of breath, I even fainted at work. The doctor suggested Plaquenil as a possible alternative, but after reading some of the comments, I don't think so. This is really frustrating and sad. Hi! I got real sick a year ago ANA 4 speckled pattern and my Rheumatologist started me on Hydroxychloriquine Plaquenil. After just a few weeks I felt wonderful. I didn't realize how sick I was until I felt normal again! Anyway, being the idiot that I am I quit taking the drug thinking maybe the lupus Plaquenil didn't work for me. Methotrexate isn't so bad if you can deal with being stupidly tired and brain foggy one day a week, a day I dub "Methotrexate Hangover Day." Start with either, and keep in mind you may have to try a few different meds before you find one that works.