This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Can plaquenil cause a rash Deschloroquine used on chloroquine resistant parasites Plaquenil how long does it take to work What Is the Chloroquine Dosage for Preventing Malaria? The usual dosage for malaria prevention in adults is 500 mg once a week. The chloroquine dose in children is based on the child's weight. Children either receive about 8.3 mg per kg of body weight about 3.8 mg per pound of body weight or the adult dose, whichever is less. For treatment of acute attacks of malaria in adults, one dose is usually taken right away, followed by half the dose 6 to 8 hours later and then half the dose once a day for the next 2 days. For prevention and treatment of malaria in infants and children, the amount of chloroquine phosphate is based on the child's weight. Treatment of uncomplicated malaria due to Chloroquine-sensitive Plasmodium species Adults An initial dose of 1 g salt = 600 mg base followed by an additional 500 mg = 300 mg base after six to eight hours and a single dose of 500 mg = 300 mg base on each of two consecutive days. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine lethal dose Chloroquine Side Effects Common, Severe, Long Term., Chloroquine MedlinePlus Drug Information Saltwater fish chloroquine compatible with metroplexHydroxychloroquine-o-sulfate Chloroquine was administered to the mice in the first group as 20 mg/kg b.w. once a day for four consecutive days. Quinine at a dose of 20 mg/kg b.w. was given to the mice in the second group for the first day and 10 mg/kg b.w. for the second to fourth day. Comparative study of chloroquine and quinine on malaria.. Chloroquine - FDA prescribing information, side effects.. Treatment of hydroxychloroquine overdose - ScienceDirect. Hydroxychloroquine and Chloroquine have a similar dose related risk assessment 10mg / kg is potentially toxic; Increasing mortality is expected at doses 30mg / kg 5 grams in adults is fatal without intervention; Children Ingestion of just one tablet can be fatal in the under 6 year olds. Clinical features Onset within 1 -2 hours. Dizziness Medscape - Indication-specific dosing for Aralen, Chloroquine phosphate chloroquine, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. The previous administration of chloroquine to normal rats resulted in a significant increase in the lethal dose of morphine and in a higher amount of conjugated morphine in the liver. No differences were found on normorphine formation in liver of treated and untreated groups.