Lupus medications can help lower long-term risks and keep symptoms under control. According to the Lupus Foundation of America, 80% to 90% of people with lupus can expect a normal lifespan with good treatment. In the 1950s, most people with lupus died within a few years of diagnosis. A combination of earlier diagnosis, better lupus medications, and more aggressive treatment, says Lisa Fitzgerald, MD, assistant professor of medicine at Harvard Medical School. Chloroquine dosage regimen Purpose of plaquenil in lupus Hydroxychloroquine is taken in tablet form, with or after food. Your doctor will advise you about the correct dose. Usually you will start on a full dose of 200–400 mg daily, and later your doctor may reduce this. When your condition is very well controlled you may be advised to take hydroxychloroquine only 2–3 times per week. The number needed to treat NNT is an epidemiological measure used in communicating the effectiveness of a health-care intervention, typically a treatment with medication. The NNT is the average number of patients who need to be treated to prevent one additional bad outcome e.g. the number of patients that need to be treated for one of them to benefit compared with a control in a clinical trial. Recommended doses of the medication vary according to the condition being treated. Rheumatoid arthritis The usual adult starting dose is 400 mg to 600 mg daily. It may take several weeks before the beneficial effects of hydroxychloroquine for the treatment of rheumatoid arthritis are seen. "I want people to have the same level of functioning that they had before they got sick," Bermas tells Web MD. Now, the goal of lupus treatment is not just to reduce the symptoms, but to maintain full function, says Bonnie Lee Bermas, MD, director of the Brigham and Women's Hospital Lupus Center in Boston. Number needed to treat hydroxychloroquine HCQ - Clinical Hydroxychloroquine, Serum, Number needed to treat - Wikipedia Hydroxychloroquine for lyme arhtritisLichen planus plaquenil Lupus is mainly treated with medicine. The types of drugs that have been used to treat lupus include NSAIDs, corticosteroids and other immune system suppressing drugs, hydroxychloroquine, and the newest lupus drug, Benlysta. Lupus medications work in different ways. Lupus Medications and Treatments. Plaquenil - Uses, Side Effects, Interactions -. Number Needed to Treat NNT - CEBM. Dosing information For the treatment of RA, hydroxychloroquine is typically taken by mouth once daily at 200-400 mg, although it can be taken at a higher dose. A loading dose of 1,200 mg daily, given for 6 weeks may decrease the time to clinical response. However, experts debate that this higher dosage may increase the risk of toxicity. Calculations. Number need to harm is calculated in the same way as number needed to treat divide 1 by the absolute risk increase. References IBIS investigators. First results from the International Breast Cancer Intervention Study IBIS-I a randomised prevention trial. Lancet 2002;37–24. Rabbie, et. al. Researchers say hydroxychloroquine can prevent or reduce the severity of the coronavirus Credit Reuters This drug, which is typically used to treat malaria, has become the first to be approved to.