Regardless of the problem, we'd like to help you find what you're looking for. A drug commonly prescribed for the treatment of primary Sjögren's syndrome was no better than placebo at relieving symptoms of dryness, pain, or fatigue over the course of 24 weeks, results of a randomized clinical trial show. Hydroxychloroquine hearing loss How long does it take for plaquenil to work Can plaquenil cause dry mouth Sulfasalazine vs plaquenil Sjogren's Syndrome Sjorgrens and Hydroxychloroquine Follow Posted 4 years ago, 5 users are following. mandy95. I have recently been diagnosed with Sjorgrens, although I believe I have had it for years. The RA has perscribed me 400mg of Hydroxychloroquine but after a month of taking the medication I noticed that I was having trouble reading. A combination of leflunomide and hydroxychloroquine significantly reduced disease activity, increased salivary flow, and improved patient-perceived health in patients with primary Sjögren’s syndrome, a pilot trial showed. Findings of the trial were revealed at the recent American College of. Hydroxychloroquine is the immunomodulatory drug most frequently used for primary Sjögren syndrome, 7 usually prescribed for patients with fatigue, arthralgia, and myalgia 8-10 rather than severe systemic manifestations. The latter symptoms are treated with corticosteroids and azathioprine, cyclophosphamide, mycophenolate mofetil, or rituximab. "In the present study, hydroxychloroquine did not demonstrate efficacy for the main disabling symptoms — dryness, pain, and fatigue — of primary Sjögren syndrome compared with placebo," the investigators write in an article published in the July 16 issue of JAMA. At 24 weeks, 17.9% of patients randomly assigned to receive hydroxychloroquine (Plaquenil, sanofi-aventis) had a 30% or greater reduction in symptoms on at least 2 of 3 analog symptom scales compared with 17.2% of patients assigned to receive a placebo, report Jacques-Eric Gottenberg, MD, Ph D, from the University Hospitals Strasbourg in France, and colleagues. Hydroxychloroquine for sjogren's syndrome Hydroxychloroquine User Reviews for Sjogren's Syndrome at., Pilot Trial in Sjögren’s Shows Potential of Leflunomide-Hydroxychloroquine Plaquenil and hyperpigmentationSpecific test for the retina when going on plaquenilHydroxychloroquine and aspirinPlaquenil and radiation therapyChloroquine phosphate abd goby OBJECTIVE To evaluate the effect of hydroxychloroquine treatment on interleukin 6 IL6, hyaluronic acid HA, and soluble interleukin 2 receptor sIL2R concentrations in the saliva and serum of patients with primary Sjögren’s syndrome SS. METHODS Fourteen SS patients treated with hydroxychloroquine 200 mg/day for 12 months were investigated in an open prospective study. Clinical. Hydroxychloroquine treatment for primary Sjögren’s.. Hydroxychloroquine for Sjögren Syndrome Symptoms - JAMA. Study Raises Questions about Sjogren's and Plaquenil. A medication called hydroxychloroquine is sometimes recommended by Sjögren's syndrome specialists as a treatment for joint pain or stiffness if other methods haven't helped. But it isn't suitable for everyone and can take several months to work. It can also cause side effects such as tummy pain and feeling sick. Although there are few reports that describe the efficacy of hydroxychloroquine for skin disease in Sjögren syndrome, hydroxychloroquine is widely used in the treatment of autoimmune skin diseases such as cutaneous lupus erythematosus. Sjögren syndrome SjS, SS is a long-term autoimmune disease that affects the body's moisture-producing glands. Primary symptoms are a dry mouth and dry eyes. Other symptoms can include dry skin, vaginal dryness, a chronic cough, numbness in the arms and legs, feeling tired, muscle and joint pains, and thyroid problems.